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Immunodeficiency due to a late component of complements deficiency
6 OMIM references -
7 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 2
Fibronectin glomerulopathy
2 OMIM references -
1 associated gene
10 signs/symptoms
Immunodeficiency due to a late component of complements deficiency
Fibronectin glomerulopathy

C5
(UniProt - OMIM)
 FN1
(UniProt - OMIM)
C6
(UniProt - OMIM)
C7
(UniProt - OMIM)
C8A
(UniProt - OMIM)
C8B
(UniProt - OMIM)
C8G
(UniProt - OMIM)
C9
(UniProt - OMIM)

INTERACTOME
ASSOCIATIONS
(click on a score value to see the evidence)
C6
C9
(0.63)
(0.63)
FN1
FN1


Citations in the biomedical literature:


Immunodeficiency due to a late component of complements deficiency
C5 C6 C7 C8A C8B C8G
C9
Fibronectin glomerulopathy
FN1



Immunodeficiency due to a late component of complements deficiency
Fibronectin glomerulopathy

Synonym(s):
- Deficiency of complement of terminal pathway
- Immunodeficiency due to a C5 to C9 component complement deficiency
Synonym(s):
- GFND
- Glomerulopathy with fibronectin deposits
Classification (Orphanet):
- Rare genetic disease
- Rare immune disease
Classification (Orphanet):
- Rare genetic disease
- Rare renal disease
Classification (ICD10):
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -
Classification (ICD10):
- Diseases of the genitourinary system -
Epidemiological data:
(no data available)
Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: variable
Average age of death: -
Type of inheritance: autosomal dominant
External references:
6 OMIM references -
No MeSH references
External references:
2 OMIM references -
No MeSH references
Fibronectin glomerulopathy

Very frequent
- Autosomal dominant inheritance
- Chronic arterial hypertension
- Edema of the legs / lower limbs
- Functional anomalies of the kidney and the urinary tract
- Hematuria / microhematuria
- Nephrotic syndrome
- Proteinuria
- Renal failure
- Renal glomerular defect / glomerulopathy

Occasional
- Intracranial / cerebral / meningeal hemorrhage


Immunodeficiency due to a late component of complements deficiency

(no data available)